If you thought those annoying little blisters were just a minor inconvenience, think again. Recent research has shed light on how the herpes simplex virus type 1 (HSV-1)—the culprit behind those cold sores—might be increasing your risk of Alzheimer’s. But don’t worry, we’ve got the lowdown on how you can protect your brain and keep those neurons firing!
Unveiling the Connection

A groundbreaking study published in BMJ Open has revealed that individuals with a history of HSV-1 infections have an 80% higher risk of developing Alzheimer’s disease (see all sources at the end of the article.) This discovery adds a new layer to our understanding of Alzheimer’s and highlights the importance of managing viral infections. But here’s the silver lining: the same study found that those who took antiviral medications to treat HSV-1 were 17% less likely to develop Alzheimer’s. That means taking control of those cold sores could be a proactive step toward safeguarding your brain health.
What You Can Do to Reduce Your Risk
- Manage Cold Sores Like a Pro: If you’re prone to cold sores, don’t just shrug them off. Talk to your healthcare provider about antiviral medications like acyclovir or valacyclovir. These meds can reduce the frequency and severity of outbreaks and might just be your brain’s best friend in the long run.
- Nourish Your Noggin: Your brain craves the right fuel. A diet rich in antioxidants (think blueberries, spinach, and nuts), omega-3 fatty acids (found in fatty fish like salmon), and whole grains can help reduce inflammation and boost brain function.
- Move Your Body: Exercise isn’t just good for your waistline; it’s a brain booster, too. Regular physical activity increases blood flow to the brain, promotes the growth of new neurons, and helps keep your cognitive function sharp.
- Keep Calm and Carry On: Chronic stress is no joke. It can wreak havoc on your brain health. Practices like yoga, meditation, and mindfulness can help you keep stress levels in check, protecting your mental well-being.
- Stay Socially Active: Maintaining strong social connections isn’t just good for the soul; it’s great for your brain. Studies have shown that social engagement can improve cognitive health and reduce the risk of dementia.
- Monitor Your Overall Health: Conditions like diabetes, hypertension, and high cholesterol are also linked to an increased risk of Alzheimer’s. Regular check-ups and managing these conditions can help keep your brain in top form
The link between cold sores and Alzheimer’s might sound like something out of a sci-fi movie, but it’s a reality we can’t ignore. The good news? You have the power to take proactive steps to protect your brain. From managing HSV-1 with antiviral medications to leading a brain-healthy lifestyle, you’re not just safeguarding your neurons—you’re setting yourself up for a vibrant future.
Stay sharp, and remember: Bee Healthy, Bee Well!
SOURCES:
https://bmjopen.bmj.com/content/15/5/e093946
https://medicalxpress.com/news/2025-05-cold-sore-viral-infection-implicated.html#google_vignette
https://newatlas.com/brain/alzheimers-dementia/herpes-simplex-1-alzheimers-risk-antiviral-medication
